Anna Sigmon

Anna Sigmon
Assistant Professor, Chemistry
Main Building, 312
25 Yearsley Mill Road
Media, PA 19063

Dr. Anna Sigmon joined the faculty at Penn State Brandywine in fall 2020. She holds both a PhD in chemistry from The University of Texas at Austin and a JD from George Washington University. Prior to working in academia, Anna worked as a patent lawyer in the private sector.

Dr. Sigmon’s current research is focused on two areas: the synthesis of bioactive small molecules and chemical education pedagogy. Her small molecule research involves the synthesis, structural elucidation and biological testing of novel, flavonoid-based compounds with potential medicinal applications. Flavonoids encompass a large group of naturally occurring compounds that possess a huge diversity of health benefits. They are found in everyday sources including chocolate, red wine and green tea. Dr. Sigmon is synthesizing a variety of flavonoid derivatives for potential anti-viral, anti-fungal and anti-aging applications.

Dr. Sigmon’s pedagogy research focuses on the development of collaborative, active learning methodologies for use in the chemistry classroom. Recently, she published an article on the use of a social annotation platform to enhance a flipped organic chemistry course by facilitating collaborative, asynchronous interactions with flipped content.

Selected publications:

Anna Sigmon and Matt Bodek. “Use of an Online Social Annotation Platform to Enhance a Flipped Organic Chemistry Course.” J. Chem. Ed.202299, 538-545.

Hemant P. Yennawar and Anna Sigmon. “Crystal structure of racemic (R/S,E)-2-(4-hydroxyphen-yl)-4-(2-phenylhydrazin-1-ylidene)chromane-5,7-diol ethanol monosolvate.” Acta. Cryst. 2022, E78.

“Enantioselective Conjugate Addition Employing 2-Heteroaryl Titanates and Zinc Reagents,” Organic Letters, 2009, pp. 4200-4203.

“Features and Applications of [Rh(CO)2Cl]2-Catalyzed Alkylations of Unsymmetrical Allylic Substrates,” Journal of Organic Chemistry, 2007, pp. 9018-9031. 

“[Rh(CO)2Cl]2-Catalyzed Domino Reactions Involving Allylic Substitution and Subsequent Carbocyclization Reactions,” Organic Letters, 2005, pp. 1661-1663.